What are the options for my 21-year old daughter who had to break a business lease on shop that she was forced to close.

You say it was a business lease,  Was your daughter the tenant, or was it a business entity she had created (i.e. a corporation or llc).  If the latter, and assuming that your daughter operated the entity properly, your daughter is not personally liable unless she personally guaranteed the obligations under the lease.  Also, depending on the jurisdiction (I don't know what the law is in NC), your daugher may not be liable for the entire unpaid rent, but only for the difference between the rent due under her lease and the amount the landlord is able to rent the space for now.   Assuming that your daughter is personally obligated  for the lease, you may still be able to reach a settlement with the landlord.  Since yur daughter is unable to pay her obligations, she may be eligible to have the debt discharged in bankruptcy.  While this is a last resort, it would also be bad for the landlord, who may accept less than the full amount to avoid it, particularly if that amount is offered by someone who is not legally obligated to pay it, i.e. a friend or family member of your daughter.