My husband is acting strangely. He abandoned his well paying business and took money from his 401k. Now he wants to withdraw more.

If your husband is acting strangley you can try to get a court order saying he is not able to deal with his own finances.  you would do this thorugh an emergency guardianship.  I think you can also contact the 401(k) company as the spouse and indicate that he should not be permitted to withdraw any fruther funds from the account.