If you can qualify under the first or second employment-based preference, you might be able to do this, but normally you can't change from a B-1/B-2 to a green card while in the U.S. You would have to consular process. You need to schedule a consultation with an attorney to see your options as you may need to change to another nonimmigrant work authorized status first.
Answered on Jun 30th, 2014 at 10:12 AM