Can someone sue you 2 years after a car wreck in which insurance paid for damages?

Anybody can sue anybody for anything, but what you're really asking is does she have a case.  Was there a settlement agreement which included a release, or some sort of agreement that the party would not seek further compensation?  If your insurer paid money to the other party, it almost certainly would have obtained such a release.  If not, the SC satute of limitations on such a claim is 3 years from the accident.