Can I donate to for profit school in the state of florida and receive a tax right off?

Your question does not specify whether you are talking about a state or federal income tax issue and the answers may not be the same. Further, I am assuming that your state tax return is filed in Michigan and not Florida since you have indicated this is a Michigan tax question. A "for profit" school is different than a qualified "non-profit" 501C3 organization. If the donation is to a qualified fund associated with the school, a federal tax deduction may be available whereas a donation to the "for profit" school itself will not qualify. If you made such donations in 2011, you may be able to claim a tax credit for the donation however, those types of deductions disappear for Michigan in tax year 2012.

It may be true on your Florida tax, although I doubt it. I certainly isn't true for your federal taxes. Only charitable contributions can be deducted, and, then, only if the "charity" is a 501(c)(3) non-profit [or a religious organization].

Good luck on the deduction. Whereas Florida may allow deductibility of such contributions for purposes of Florida taxes, the IRS sets the rule as to deductibility of donations and, if the school or entity does not qualify the donation will not be deductable from you federal and Michigan tax.